The prospective PhD candidate will collaborate with team members who are specialized in bioengineering (Twente), transcriptomics, proteomics and computational biology (Nijmegen, Twente) as part of a recently awarded NWO OC-ENW-XL Consortium “HeartEngine”. The PhD candidate position is available immediately. In this project we will use innovative ultra-high throughput in-air-microfluidics for the generation of functional cardiac organoids that display self-organization and patterning, comparable to the human heart. As a member of the team, you will be involved in the generation of human pluripotent stem cell fluorescent reporter lines using CRISPR-Cas9 genome editing, differentiation of hPSC to multi-layered cardiac organoids using in-air-microfluidics. You will use high content imaging to study the self-organization and molecular regulation of cardiac organoids.
Information and application
For questions about the position, please contact Robert Passier, Professor, at robert.passier@utwente.nl
Practical information and applying
You can apply until 31st of May 2023, exclusively using the button below. Kindly address your application to Robert Passier. Please fill in the application form and attach the following documents:
- A letter of motivation, emphasizing your specific interest and motivation,
- Your CV including the contact details of three references.
- Academic transcript of B.Sc. and M.Sc. education.
An interview and a scientific presentation will be part of the selection procedure.
About the department
The PhD-candidates will work in the Passier Lab, which is part of the department of Applied Stem Cell Technologies AST. We use stem cell and molecular technologies, organ-on-chip-devices, advanced tissue engineering to emulate and understand organ development and function in health and disease. We AST is part of the Technical Medical Centre of the University of Twente, which is widely recognized for its cutting-edge developments in biomedical technology and advanced biomanufacturing.
About the organisation
The Faculty of Science & Technology (Technische Natuurwetenschappen, TNW) engages some 700 staff members and 2000 students in education and research on the cutting edge of chemical technology, applied physics and biomedical technology. Our fields of application include sustainable energy, process technology and materials science, nanotechnology and technical medicine. As part of a people-first tech university that aims to shape society, individuals and connections, our faculty works together intensively with industrial partners and researchers in the Netherlands and abroad, and conducts extensive research for external commissioning parties and funders. Our research has a high profile both in the Netherlands and internationally and is strengthened by the many young researchers working on innovative projects with as doctoral candidates and post-docs. It has been accommodated in three multidisciplinary UT research institutes: Mesa+ Institute, TechMed Centre and Digital Society Institute.
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