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Post-Doc position in Systems Biology

Post-Doc position in Systems Biology

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  • Hi! Are you my
    new colleague?
    Jennifer Herek
  • Hi! Are you my
    new colleague?
    Marcel Karperien
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    Sonia García Blanco
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    new colleague?
    Pieter Tuchter
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    new colleague?
    Monica Morales Masis
  • Hi! Are you my
    new colleague?
    Srirang Manohar
  • Hi! Are you my
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    Mireille Claessens

Key takeaways

  • Hours 40 hr.
  • Salary indication € 3,413 - € 4,670
  • Deadline 15 Dec 2022

We offer a Post-Doc position in Systems Biology at the University of Twente (UT)

The Department of Developmental BioEngineering at the University of Twente (Enschede, the Netherlands) is looking for a computational modeler to describe and predict factors for better stem cell differentiation for heart tissue engineering applications. This project will be performed in close collaboration with the department of Mathematics of Imaging & AI (MIA) at the University of Twente.

The Challenge

Current animal and cell culture models are not accurate enough to predict the efficacy and toxicity of drugs. In this research project, titled ‘Advanced bioengineering strategy for production of human miniature hearts’, a multidisciplinary team consisting of (developmental) biologists, bioinformaticians, and mathematicians will encapsulate human stem cells in hollow miniature spheres made from hydrogel and use single cell OMICs analysis to make digital twins of the miniature hearts. The digital twins generated in this project allow investigating heart development and predicting the response of the heart to medication.

Your profile

We look for a highly motivated, enthusiastic researcher who is driven by curiosity and:

  • Has, or will shortly acquire, a PhD degree in (Applied) Mathematics, Systems Biology, or Biomedical Engineering, Bioinformatics or a related field;
  • Has experience with mathematical modelling and analysis with large-scale simulation tools and/or bifurcation analysis;
  • Has a strong interest in systems biology;
  • Experience with analysis of big data (transcriptomics, proteomics) and / or heart development will be considered a benefit;
  • Is a team player with good communication skills;
  • Has demonstrated scientific creativity that has preferably resulted in recent and relevant high-quality scientific publications in international journals
  • Is proficient in English, both spoken and written.
  • Has an interest in contributing to the education of Ba-Ma students
  • Experience in managing projects and writing project proposals will be considered a benefit.

Our offer

  • A fulltime Post-Doc position;
  • Initially employed for two years, after which your position can be extended;
  • Full status as an employee at the UT, including pension and health care benefits;
  • Gross monthly salary between € 3.557,- and € 4.670.- (depending on experience and qualifications)
  • The University of Twente provides excellent facilities for professional and personal development, a holiday allowance and an end-of-year bonus;
  • A solid pension scheme;
  • A lively and green campus with many facilities for sports and other extracurricular activities;
  • Excellent facilities for professional and personal development.
  • Your main responsibility will be to carry out research, but you will be given the opportunity to acquire some teaching experience and supervise students in Master and Bachelor projects as well.
  • Total of 41 holiday days in case of full-time employment
  • The terms of employment are in accordance with the Dutch Collective Labour Agreement for Universities (CAO)

Information and application

Are you interested to be part of our team? Please send your application and include:

For inquiries about this position and our offer you can contact Janine Post, PhD (j.n.post@utwente.nl). An application for this position should be accompanied by motivation and curriculum vitae, including a list of publications (when applicable) and can be submitted via                  website

KEY WORDS: mathematical modeling, regenerative medicine, computational modeling, Heart development, stem cells, etc.

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About the department

Department of Developmental BioEngineering

The department of Developmental BioEngineering is a research group with a highly international character. The main goal of this group is to investigate novel and challenging technologies in the field of Regenerative Medicine, which can be used for tissue repair. Research focuses on i) Fundamental aspects of joint and cartilage homeostasis, ii) Cell therapy for treatment of joint disorders, and iii) Injectable, in situ gelating extracellular matrices for soft tissue repair, iv) computational models for tissue development and homeostasis. website

The project will be performed in close collaboration with the department of Mathematics of Imaging & AI (MIA) at the same university (UT). This department focuses on topics in the area of dynamical systems, numerical analysis and scientific computing, and systems and control, and in particular, their relation with data science.                                          website

About the organization

The Faculty of Science & Technology (Technische Natuurwetenschappen, TNW) engages some 700 staff members and 2000 students in education and research on the cutting edge of chemical technology, applied physics and biomedical technology. Our fields of application include sustainable energy, process technology and materials science, nanotechnology and technical medicine. As part of a people-first tech university that aims to shape society, individuals and connections, our faculty works together intensively with industrial partners and researchers in the Netherlands and abroad, and conducts extensive research for external commissioning parties and funders. Our research has a high profile both in the Netherlands and internationally and is strengthened by the many young researchers working on innovative projects with as doctoral candidates and post-docs. It has been accommodated in three multidisciplinary UT research institutes: Mesa+ Institute, TechMed Centre and Digital Society Institute.

About the TNW Faculty

Curious about what the Faculty of Science and Technology (TNW) stands for? Check out the Science and Technology website for more information.

job that matters

Create new opportunities for yourself, your colleagues and our society. Scientist or teacher, administrator or facilitator, thinker or doer, energetic leader or silent support – your work at the University of Twente matters. And you too!

How to apply

Step 1

Apply.
When you see a vacancy that appeals to you, you can apply online. We ask you to upload a CV and motivation letter and/or list of publications. You will receive a confirmation of receipt by e-mail.

Apply now

Step 2

Selection.
The selection committee will review your application and you will receive a response within 2 weeks after the vacancy has been closed.

Step 3

1st interview.
The 1st (online or in person) meeting serves as an introduction where we introduce ourselves to you and you to us. You may be asked to give a short presentation. This will be further explained in the invitation.

Step 4

2nd interview.
In the second interview, we will further discuss the job content, your skills and your talents.

Step 5

The offer.
If the conversations are positive, you will be made a suitable offer.

Want to know more?

Post, J.N. (Janine)

Post, J.N. (Janine)
Associate Professor

Post, J.N. (Janine)
Associate Professor

Do you have questions about this vacancy? Then you can contact Janine for all substantive questions about this position and the application procedure. For general questions about working for the UT, please refer to the chatbot.

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