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  2. PhD Position - Developing methods for multi-disease test evaluation

PhD Position - Developing methods for multi-disease test evaluation

Are you passionate about crafting the future of healthcare? If you want to improve health and health system outcomes by developing crucial test evaluation methodology then this position could be perfect for you!

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    Theodora Spirova
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    Ipek Topan
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    Abhishta Abhishta
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    Tanya Bondarouk
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    Hannie Lensink

Key takeaways

  • Hours
    38 - 40 hr.
  • Salary indication
    Salary gross/monthly
    based on full-time
    € 3,059 - € 3,881
  • Deadline
    5 Jul 2026

Background and Challenge

In healthcare, numerous "multi-disease tests" are quickly appearing. They aim to identify multiple diseases using one blood sample or medical image. These tests can find diseases early, before symptoms develop. However, they often produce false positives, indicating disease when none is present. Although methods exist to balance early diagnosis benefits and false positive risks for single disease tests, such methods are not available for multi-disease tests.

In the MERIT project, we will develop new quantitative appraisal methods for multi-disease tests. See link. These methods will guide policymakers and physicians in making informed choices about acquiring and applying these novel tests. Through this research, you will contribute to the healthcare of the future and positively affect the lives of thousands!

Job description

We seek two highly motivated PhD candidates for this project, one at the University of Twente and one at the Amsterdam UMC. This vacancy is for the position at the University of Twente, within the innovative Health Technology and Services Research (HTSR) section at the Faculty of Behavioural Management and Social Sciences. This section includes about 35 researchers and focuses on personal and professional growth. There is also ample opportunity for social interaction. In this project, you will work with partners at Amsterdam UMC and Radboudumc. You will start by building on existing methods for evaluating single tests. Then, you will create a framework for health and economic evaluation of multi-disease tests, and test this using AI applications in radiology as a practical case study.

Your profile

You are an enthusiastic researcher driven by curiosity and:

  • Have an affinity with statistical or mathematical modeling, and (some) programming experience, preferably in R or Python;
  • Have, or will shortly acquire, a quantitative master's degree (for example, in Health Economics, Econometrics, Technical Medicine, Industrial Engineering, Biomedical Engineering, Applied Mathematics/Statistics, or Computer Sciences);
  • Enjoy working in an interdisciplinary environment;
  • Possess good communication skills and are proficient in English, both spoken and written. Dutch proficiency is not required but considered an advantage.

Our offer

  • A full-time position for four years, with a qualifier in the first year, and the flexibility to work (partially) from home.
  • Your salary and associated conditions are in accordance with the collective labour agreement for Dutch universities (CAO-NU).
  • You will receive a gross monthly salary ranging from € 3.059 (first year) to € 3.881,- (fourth year)
  • There are excellent benefits including a holiday allowance of 8% of the gross annual salary, an end-of-year bonus of 8.3%, and a solid pension scheme.
  • A minimum of 232 leave hours in case of full-time employment based on a formal workweek of 38 hours. A full-time employment in practice means 40 hours a week, therefore resulting in 96 extra leave hours on an annual basis.
  • Free access to sports facilities on campus.
  • A family-friendly institution that offers parental leave (both paid and unpaid).
  • You will have a training programme as part of the Twente Graduate School where you and your supervisors will determine a plan for a suitable education and supervision.

Information and application

Please submit your application using the “Apply now” button, and include:

This vacancy will remain open until July 5, 2026, at the latest. Upon receiving applications, potentially suitable candidates will be invited for an interview, and the vacancy will be closed as soon as a candidate has been found.

Additional information about this position can be acquired via email from Prof.Dr. Erik Koffijberg (h.koffijberg@utwente.nl, from April 28th onwards) or from Prof.Dr. Mariska Leeflang (m.m.leeflang@amsterdamumc.nl).

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About the department

At HTSR, interdisciplinary expertise is brought together to aid decision-making on health innovation development, evaluation, optimization, and implementation. Research concentrates on quantitative analyses that underpin strategies to enhance the efficiency and sustainability of healthcare systems. The HTSR section forms part of the Faculty of Behavioural, Management and Social Sciences BMS and the Technical Medical Center TechMed, a leading innovation hub of the University of Twente.

We are an equal opportunity employer and value diversity at our University. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process. Please contact us to request accommodation.

About the organisation

At the Faculty of Behavioural, Management and Social Sciences (BMS), we unite the worlds of people and technology to address today’s complex societal challenges. We are passionate about understanding human behaviour, fostering responsible innovation, and designing solutions that create societal value. Our educational programmes span disciplines such as Psychology, Business Administration, Public Administration, Communication Sciences, Philosophy, Educational Sciences, and Health Sciences. Through our bachelor’s and master’s degrees, Professional Learning & Development programmes, and interdisciplinary research themes – including Emerging Technologies & Societal Transformations, Resilience, Smart Industry, Learning, and Health – we empower students and researchers to make a positive societal impact.

At BMS, we combine critical thinking with practical action. From advancing sustainable mobility with innovations like the world’s most efficient hydrogen car to shaping policies that promote digital inclusion, our work contributes to a healthier, fairer, and more sustainable future. Whether it’s exploring how technology influences human behaviour or leveraging data and innovation to transform industries and communities, we ensure that technology serves people – and not the other way around.

As an employer, BMS offers a vibrant, inclusive, and entrepreneurial environment where you can thrive personally and professionally. Join us and become part of a forward-thinking community that equips you to shape the future – for yourself and society. With us, you will become part of a leading technical university with increasing, positive social impact.

Want to know more?

Koffijberg, H. (Erik)

Koffijberg, H. (Erik)
Full Professor

Koffijberg, H. (Erik)
Full Professor

Do you have questions about this vacancy? Then you can contact Erik for all substantive questions about this position and the application procedure. For general questions about working for the UT, please refer to the chatbot.

How to apply

Step 1

Apply.
When you see a vacancy that appeals to you, you can apply online. We ask you to upload a CV and motivation letter and/or list of publications. You will receive a confirmation of receipt by e-mail.

Apply now

Step 2

Selection.
The selection committee will review your application and you will receive a response within 2 weeks after the vacancy has been closed.

Step 3

1st interview.
The 1st (online or in person) meeting serves as an introduction where we introduce ourselves to you and you to us. You may be asked to give a short presentation. This will be further explained in the invitation.

Step 4

2nd interview.
In the second interview, we will further discuss the job content, your skills and your talents.

Step 5

The offer.
If the conversations are positive, you will be made a suitable offer. If applicable, we will sign you up for screening.

Your Colleagues

About the BMS faculty

Curious about what The Faculty of Behavioral, Management and Social sciences (BMS) stands for? Check out the BMS website for more information.

A job that matters

Create new opportunities for yourself, your colleagues and our society. Scientist or teacher, administrator or facilitator, thinker or doer, energetic leader or silent support – your work at the University of Twente matters. And you too!

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