Faculty of Behavioral, Management and Social sciences (BMS). The focus at this faculty is on Psychology, Business Administration, Public Administration, Communication Sciences, Philosophy, Educational Sciences and Health Sciences.

The Center for Educational Support (CES) provides all study support activities of the University of Twente.

The Campus & Facility Management (CFM) department is responsible for all campus facilities.

Faculty of Electrical Engineering, Mathematics and Computer Science (EEMCS) uses mathematics, electrical engineering and computer science for the ongoing development of Information and Communication Technology.

Faculty of Engineering Technology (ET). The focus at this faculty is on Civil Engineering, Industrial Design and Mechanical Engineering.

The Finance department (FIN) provides financial support for the organization.

The Faculty of Geo-Information Science and Earth Observation (ITC) aims to enable society to effectively develop and use geo-information and earth observation knowledge and technology for agricultural and environmental sustainability.

The Marketing & Communications Department (M&C) uses marketing and communication tools to ensure an optimal connection between the university and its internal and external target groups.

Faculty of Applied Sciences (TNW, Science & Technology). The focus at this faculty is on 3 domains, namely Chemistry, Health and Physics.